Background Lesions In Laboratory Animals: A Color Atlas, 1e Download Free (EPUB, PDF)
Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas.over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies
Hardcover: 256 pages
Publisher: Saunders Ltd.; 1 edition (December 9, 2011)
Language: English
ISBN-10: 070203519X
ISBN-13: 978-0702035197
Product Dimensions: 0.5 x 9 x 11.5 inches
Shipping Weight: 1.8 pounds (View shipping rates and policies)
Average Customer Review: 3.0 out of 5 stars See all reviews (1 customer review)
Best Sellers Rank: #780,938 in Books (See Top 100 in Books) #145 in Books > Textbooks > Medicine & Health Sciences > Veterinary Medicine > Small Animal #241 in Books > Medical Books > Veterinary Medicine > Small Animal Medicine #398 in Books > Textbooks > Medicine & Health Sciences > Veterinary Medicine > General
This book covers subject material that is quite important to drug development scientists and those who model toxicity in animal studies. Background lesions can confound study interpretations, and I have found it useful in a few projects already. Given the high cost of this reference, though, I did expect more substance. The reference suffers two deficiencies that limit utility; perhaps these can be addressed in future editions. First, the illustrations are too small. Detail and perspective (surrounding tissue) are very important in morphology, and the small illustration size limits both. Second, more written perspective and interpretation based on published studies would be helpful in understanding what is known about the cause and incidence of such lesions, and where they may be exacerbated by xenobiotics. What's included is a good foundation but insufficient in detail. Despite these shortcomings, this is a useful though expensive reference.
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